LONDON: Asthma is very distressing and now there has been a major breakthrough in the long-term treatment of this disease.
Every year, millions of people worldwide, including in Pakistan, succumb to the excruciatingly painful condition of asthma.
Researchers from Imperial College London and the University of Aston have developed a novel way for identifying the underlying cause of asthma. In studies using mice, almost all signs of asthma vanished, and their airways stayed healthy for two weeks.
Steroids are currently being used to treat it, and they provide momentary relief. However, the pericyte, a specific kind of stem cell, has been taken into account in this situation by Dr. Jill Johnson of Easton University and her associates. which is found in the blood vessel's inside lining. When dust or any other cause causes an asthma attack, the pericytes reach the wall of the airways.
One type of protein CXCL12 was found to translocate to pericytes. For this, scientists have created a molecule called LIT 927 that blocks its signal. It was injected into the nose of a rat. Mice that were sprayed with them experienced significant relief of asthma symptoms within a week. On the other hand, LIT 927 treatment also preserved airway aesthetics. Even the airways of the asthmatic mice became exactly like those of the healthy mice.
Now scientists are doing more research on it. They believe that after the effect on mice, its benefits may also be seen in people
0 Comments